Volbella is a hyaluronan based filler with smaller particles than Voluma or Juvederm Ultra Plus. It is manufactured and FDA approved to be injected where a filler would be needed to be injected superficially in certain areas, such as under fine lines, or in the lips. In Europe, it is approved to be injected in the depressed areas under the eyes as well.
A small percentage of patients who had had Restylane injected under their eyes would notice puffiness under their eyes months after the area appeared perfect. The slightly noticeable puffiness would need to be injected with the enzyme, Vitrase, to dissolve some of the filler. That puffiness was due to the breakage of the Restylane particles by the enzyme that is ordinarily present within the skin, resulting in greater surface area on the Restylane particles to absorb water to themselves. Volbella is manufactured in a manner that it would absorb much less water to itself than Restylane. That is a probable advantage for patients who have had the volume under their eyes restored with Restylane, and months later experienced puffiness.