Platelet Rich
Plasma (PRP)

The Elixir of Youth: Platelet Rich Plasma

Humans keep on discovering, or achieving whatever someone has imagined. Did someone mention “The Elixir of Youth?” The regenerative factors that are stored within our platelets appear to function as the elixir of regeneration and youth.

Platelets are cell fragments that are split off of megakaryocyte cells which reside in our bone marrows. The stored repair and regenerative mediators within the platelets are employed in Platelet Rich Plasma (PRP) treatment.

When a capillary is severed, a number of protein molecules that are produced by the liver and the bone marrow, which normally float within the plasma (the liquid acellular portion of the blood), are transformed, and cross-linked to form a sticky lattice that is called the fibrin. In between the strands of fibrin, the pebble-like platelets, which normally float in the blood, become embedded to form a plug, i.e., a blood clot. Invariably, at the site of the laceration of a capillary, repair and regeneration is needed. Platelets contain the molecules that facilitate repair and regeneration.

 

Burns and non-healing wounds. PRP injection under the burn or wound expedites healing significantly, results in a better appearance of the final healed area.

Sexual organ, and function enhancement (PRP Rhino Boost). The penis is a very porous organ. When PRP is injected at one spot of the tissue the platelets distribute throughout the organ. The erectile enhancement is noted incrementally day by day over the next months. No human being could tolerate a needle piercing through his genitalia. The area is numbed by a numbing gel, and numbing injections at distant sites in the groin to deaden the nerve fibers that reach the penis, without injecting the penis with anesthetics.
Many women suffer from slight or mild incontinence as a result of prior childbirth. Female genital treatments with PRP can result in increased muscle tone of the vaginal wall and pelvic floor muscles, thus reversing the issue. In addition, as a result, women notice well-appreciated sensitivity of the genital area.

Neck and V of the chest. Three monthly treatments with PRP, along with microneedling and sugar-based fillers (hyaluronic acid fillers, such as Restylane, or Juvederm) can result in marked natural restoration of the neck and chest. Obviously, results vary in different people, but the great majority notice a difference after the third session.

Breast restoration and enhancement. Most women notice alteration in the their breasts after the nursing period is over. PRP treatments result in restoration of the suppleness of the breasts in great majority of women.

Stretch marks. PRP has been shown to to help improve the appearance of stretch marks in the majority, but not, all the patients that were treated. Here is a link to a study, http://onlinelibrary.wiley.com/wol1/doi/10.1111/jocd.12160/abstract.

How Much Blood is Drawn for This Procedure?

A single tube of 22 ml is drawn for a scalp treatment. 11 or 22 ml for face treatment, and 22 ml plus another 11 ml for the face, neck, and décolleté areas. Just to give you an idea of the significance of the blood loss, a healthy woman in her twenties loses 50 ml of blood over her monthly period. 500 ml of blood is drawn when a healthy person donates blood.

Is There Any Chance of Contamination?

AN Patel and colleagues studied the effect of pouring PRP on chest wounds after cardiothoracic surgery in 2000 patients over seven year period. Their article was published in the Journal of Cardiothoracic surgery in April of 2016, the the pubmed link is https://www.ncbi.nlm.nih.gov/pubmed/?term=prp+cardiothoracic+infection. The PRP treated group developed much less infections than the control group.A company by the name of Eclipse has made a sterile kit, and accessories that make it possible to perform the procedure sterilely. Dr. Silvers became well familiar with the sterile technique as a fourth year Yeshiva College student when he used to prepare cell cultures in a research laboratory at Columbia Medical school. He applies the sterile technique principles that he learned in the research lab to perform the PRP procedures at his office. Dr. Silvers treats one PRP patient at a time to leave no room for cross injecting patients’ blood product specimens.

Is there any chance of scarring, or worsening a scar? None that has been reported as of 2017. We do not see why it would promote scarring or exacerbate a scar.

How long will it take for a patient to perceive an effect? I depends on the site of injection, the condition of the patient, and what is being treated. The penile PRP treatment induces noticeable improvement days after one treatment, but for most other sites that the body is expected to lay down new collagen fibers and other soft tissue components, it might take three to four sessions, and about three to four months to see a difference.

What percentage of people it doesn’t work on? The current notion among doctors is that it works on almost all patients, but to various degrees. The nuances of of which patient would be the ideal candidate, and the approximate percentage of patients who would respond to a specific PRP preparation device or method is being worked on. Since the 1990’s we have witnessed the development of various PRP methods and evolution of each method or device. Therefore, the data that was obtained on previous methods of PRP preparation may not apply to, for instance, the current Eclipse PRP device kit.

Besides contamination, are there any other adverse effects reported for PRP? As of October of 2017, contamination and infection has not yet been reported for PRP that is prepared through the Eclipse system, or any other. I think that is the case because platelets contain molecules that are anti-microbials, and those molecules increase blood flow to the area. The regrowth and regenerative factors that are within platelets interact with the control mechanisms that are in place already within tissues, and I think that is why there has not been a case of overhealed scar, or overgrowth in any shape or form. I will update this paragraph if I come across any reports of unwanted effect from platelet rich plasma treatment.

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